Acupressure Points: A Practical Guide

The most useful pressure points for headaches, stress, sleep, and nausea — where to find them, how to use them, and what the evidence says.

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The hardest part of acupressure is usually location accuracy. Descriptions like "two finger-widths below the kneecap" are consistent across traditional texts but can be hard to translate to your specific anatomy. This guide focuses on the highest-value points — the ones with the most practical use and the strongest evidence base — and gives you clear, anatomical instructions for finding each one.

No mystical frameworks required, though the traditional point names are included because they're the consistent terminology you'll find in any further reading.

How to Apply Pressure

Before getting into specific points, the basic technique:

For Headaches — LI 4 (Hegu, "Union Valley")

Large Intestine 4 · Hegu

Where it is

On the back of the hand, in the fleshy webbing between the thumb and index finger. Place your other thumb on the highest point of the muscle mound that rises when you bring your thumb and forefinger together, then relax your hand. That's LI 4.

Technique

Press firmly with the opposite thumb, angling pressure toward the bone of the index finger. A dull ache radiating toward the wrist or fingers confirms you've found the right spot. Hold for 1–2 minutes, then switch hands.

Research notes

LI 4 is one of the best-studied acupressure points. A 2011 systematic review in Cephalalgia found acupuncture (same point) was comparable to prophylactic drug therapy for reducing migraine frequency. Acupressure at LI 4 has shown modest but consistent effects on tension headache in multiple smaller trials. It appears to activate descending pain modulation pathways — the same mechanism as some pain medications, but via neural signalling rather than pharmacology.

Caution: LI 4 is traditionally contraindicated during pregnancy — it's used in some midwifery protocols to stimulate uterine contractions. Avoid if pregnant.

For Headaches & Neck Tension — GB 20 (Fengchi, "Wind Pool")

Gallbladder 20 · Fengchi

Two hollows at the base of the skull, on either side of where your neck meets the back of your head. Run your fingers up from the back of your neck — when you reach the base of the skull, you'll feel two small depressions on either side of the central ridge. Those are GB 20.

Use both thumbs simultaneously, pressing upward and inward toward the base of the skull. Tilt your head slightly back. Hold for 1–2 minutes with eyes closed. This point is particularly effective for headaches that originate at the back of the head or neck, and for tension that builds during long periods of screen time.

Suboccipital muscles attach very close to GB 20, and the point overlaps with trigger zone territory that osteopathic and physiotherapy literature independently identifies as a key treatment site for cervicogenic headache. The neuroanatomy and the traditional location point to the same place.

For Nausea — PC 6 (Neiguan, "Inner Pass")

Pericardium 6 · Neiguan

Finding the point

Turn your forearm palm-up. Place three fingers across your wrist, starting from the wrist crease. PC 6 is just above your top finger, between the two central tendons (flexor carpi radialis and palmaris longus). Press down — you should feel a mild ache or tingling sensation.

How to use it

Apply moderate, sustained pressure with your thumb or index finger. For travel sickness, stimulate before and during travel. For chemotherapy-related nausea, stimulation before and after treatment sessions has the best evidence. Sea-Band acupressure wristbands (available at every Shoppers Drug Mart in Canada) use a plastic bead to maintain continuous pressure on PC 6 — convenient for motion sickness during long drives or flights.

What the studies show

This is the strongest evidence point in all of acupressure. A 2015 Cochrane review by Ezzo and colleagues found P6 stimulation significantly reduced nausea incidence in multiple clinical contexts including postoperative nausea and chemotherapy-induced nausea. The mechanoreceptors at this site connect to vagal pathways that modulate gastric motility. The evidence is strong enough that many Canadian hospitals include acupressure wristbands in post-surgical care kits.

For Stress and Anxiety — PC 6 Companion: HT 7 (Shenmen, "Heart Gate")

Heart 7 · Shenmen

Anatomy

On the wrist crease, at the ulnar side — the pinky side of your wrist. Feel for a small hollow just inside the pisiform bone (the small round bone at the base of your pinky-side wrist). That's HT 7.

Pressure and timing

Light to moderate pressure — this point doesn't need aggressive stimulation. Use the pad of your thumb. Hold for 1–2 minutes, breathing slowly. Works well as a pre-sleep ritual in bed, or during anxious moments.

Evidence base

HT 7 has been studied primarily in elderly hospital patients and people with insomnia. A 2015 systematic review in the Journal of Alternative and Complementary Medicine found significant reductions in sleep-onset latency with HT 7 stimulation vs. sham or no treatment. The effect sizes were modest but consistent. Outside of hospital populations, the evidence is thinner — but the risk is essentially zero, so it's worth trying.

Also useful for anxiety: slow diaphragmatic breathing combined with HT 7 stimulation. The combination activates the parasympathetic nervous system through multiple channels simultaneously — point stimulation, breath pacing, and the focused attention of the practice itself.

For Back Pain — BL 40 (Weizhong, "Commanding Middle")

Bladder 40 · Weizhong

Finding it

Exactly in the centre of the crease on the back of the knee — the popliteal crease. Sit down and reach behind your knee. The point is in the middle of the hollow, between the two tendons you can feel on either side.

Self-application

Two-finger pressure directly into the crease. This is most effective for acute low back spasms — stimulate while sitting in a chair, pressing for 1–2 minutes per side. The effect seems to work through referred sensation pathways rather than local tissue effects, which is why pressing behind the knee can ease pain in the lower back.

Supporting research

BL 40 is the most commonly used point in acupressure protocols for lower back pain. A 2014 study in Evidence-Based Complementary and Alternative Medicine found BL 40 stimulation reduced pain intensity scores and muscle tension in participants with chronic lower back pain. Combined with the stronger evidence base for lower back acupressure in general, this is one of the more reliable applications. See our back pain guide for a more complete protocol.

For Sleep — SP 6 (Sanyinjiao, "Three Yin Intersection")

Spleen 6 · Sanyinjiao

SP 6 sits on the inside of the lower leg, four finger-widths above the inner ankle bone (medial malleolus), just behind the tibia. Find the ankle bone, place four fingers above it, and press inward against the back edge of the shin bone — there's usually a distinct tenderness when you've found it.

Use moderate pressure for 2–3 minutes. Many practitioners consider this the most versatile point in the system — it's used for sleep, stress, menstrual irregularity, and digestive issues. For sleep, stimulate 30–60 minutes before bed, pairing it with slow exhale-lengthened breathing.

Pregnancy caution: SP 6 is traditionally contraindicated during pregnancy. Along with LI 4 and BL 60, it's used in midwifery labour-induction protocols. If pregnant, avoid these three points unless under practitioner guidance.

When NOT to Use Acupressure

Acupressure is generally low-risk, but there are real situations to avoid:

Combining Points and Consistency

You don't need to stimulate every point listed here. A more useful approach: pick two or three points most relevant to your primary complaint and work them consistently for two weeks. Daily five-minute sessions produce more meaningful results than a single twenty-minute session once a week.

For passive, ongoing stimulation while relaxing or watching TV, an acupressure mat adds broad back coverage with minimal active time investment. See our guide to the best acupressure mats in Canada for options across different price points.

For condition-specific point protocols, see the headache guide, back pain guide, and anxiety and stress guide.